American Express Online Casinos 2025

We thoroughly check each casino for license, software quality and reliability of payment systems, including American Express. We use selection criteria to choose reliable sites:

• Transparency and Security. The first point of evaluation is whether the specific online casino has a license. Only licensed sites that operate fully make it into our ratings. Most often, casinos operate under licenses from Malta, Curaçao, the United Kingdom, and other jurisdictions;

• American Express Integration. The next factor is the degree of integration of the payment system into the online casino. Players should not encounter any difficulties when making transactions using the bank card, withdrawing their winnings, etc.;

• Casino Bonuses and Promotions. The next evaluation criterion is the available bonuses in the online casino and the conditions under which they are provided. It is important that the casino does not have any restrictions on activating bonuses when making deposits using an American Express card;

• Game Selection and Quality. We also pay attention to the available games in the online casino, their quality, and accessibility for players from different countries. It is a plus if a demo mode is available to players. With it, you can evaluate various games without risking anything at all;

• Customer Support. We also check the work of the support service. Players should have access to several ways to contact customer support, and it is a plus if there is a 24/7 chat through which you can quickly get an answer to any question.

There are a lot of things to think about that will affect how you play and enjoy the games. To help you make the best decision, consider the following advice:

• American Express Fees. The payment system has higher fees compared to other methods. Fees may vary for gold, platinum, and other types of cards;

• Casino Fees. Casinos may also charge additional fees for transactions using a bank card. This could be either a certain percentage or a fixed amount for each transaction conducted;

• Transaction Limits. Deposit and withdrawal limits vary depending on the payment system and the specific online casino. This mainly depends on the type of card the player owns as well as their status in the particular online casino. Many gambling sites allow increasing the transaction amount upon reaching a certain status in the VIP program;

• Comparison with Traditional Methods. When comparing the payment system to other payment methods, such as Visa and Mastercard, it has higher fees. Additionally, the processing speed may be slower compared to e-wallets.

If you are choosing an online casino that accept American Express on your own, you should consider several key factors to avoid making a mistake with your choice:

• Read Casino Reviews. Study the online casino reviews available on our site to choose the most reliable and proven gambling site for yourself;

• Check for Bonus Compatibility. Look at what bonuses the online casino offers to players. It is a plus if you can activate additional bonus offers for deposits made with American Express bank cards;

• Compare Fees and Limits. The next factor you should evaluate is what limits are set in a particular online casino. Pay attention to the fees charged for deposits and cashouts. It is a plus if there are no additional deductions, allowing you to play with the full amount you deposit into your balance;

• Security. Assess how the security of players is ensured in a particular online casino. It is important to have encryption certificates that will prevent data leaks and access to them by third parties;

• Understanding American Express. You should also ensure that you understand how American Express cards work and that you will not encounter any difficulties when topping up your account.

We could compare American Express to alternative payment methods like debit cards, digital wallets, prepaid cards, or cash. Learn the table to know about the difference.

Our team thoroughly tested the most reliable casinos accepting American Express. After estimating their bonus offers, gaming libraries, and conditions for making actual money transfers via bank cards, we selected the tops and have a few recommendations for our readers. Examine our research of the 5 best online casinos with American Express to sign up for the most suitable site!

MyChance

Bethard Group Limited launched MyChance in 2017. It’s friendly to bank card deposits, which can be spent on top slots like Bandit Bust Bonus Buy, Lion Coins Hold & Win, and other tops. This best AmEx-accepting online casino is supplied by RNG-proven brands like Belatra, 3 Oaks, and 1x2 Gaming, and you can use convenient filters to sort this software. Bank card transactions are fast and suitable for low $10 deposits for low-rollers and significant limits up to $5,000 for those looking for longer gaming sessions.

SuperSlots

Here’s one of the American Express casino sites where the welcome pack is as massive as $6,000. Your bank card deposit will provide you with access to many game categories, such as slots, live, and specialty games. The section with new games hosts top slots like Super Nova, Kitty Carnival, and Leprechaun’s Village. It’s also among casinos with American Express, where gamblers can experience crash games like Skyward. Please note that you can deposit $25 to $2,500 via this bank card.

VegasPlus

Since its inception in 2019 by Play Logia N.V., Vegas Plus has joined the list of top American Express casinos due to its extensive collection of instant-win games like Plinko and Coin Miner. You can deposit $15 to $1,000 per transaction, but remember that withdrawals start at $100. The first deposit will give you up to $2,250 + 100 FS and 100% Insurance. Additionally, we praise this AmEx casino online for the extensive VIP program with Bronze to Red Diamond statuses and extra perks like a birthday bonus.

CherryJackpot

Operated by Entertainment Software Group N.V., Cherry Jackpot will suit gamblers searching for enormous bonuses for their bank card deposits. Your AmEx casino deposit upon registration can bring 400% up to $8,000, while regular promotions include the 300% cryptocurrency special and personal offers by request. Its top games include Mega Monster and Magic Forest: Spellbound. As for the online payment limits at this casino with American Express, consider the $35 minimum deposit and the $200 to $4,000 withdrawal cap.

DuckyLuck

Another top on our list is Ducky Luck. Feel free to make an AmEx casino deposit upon sign-up and get 500% up to $2,500 + 150 Free Spins. Its software collection has categories for new games, slots, table games, live, and jackpot titles. Players can launch Hail Caesar, Mythic Wolf, and Bigger Cash for a safe AmEx gambling experience. Furthermore, there is an extensive large collection of RNG tables, such as Blackjack Multihand.

American Express is a popular payment method, but many other quite popular options exist. So why would you choose the casinos that accept American Express to make your real money online bets? How do you make online deposits and withdraw money from such casinos if you were lucky enough to win?

We'll try to find the answers to all these essential questions in this section, but there is one thing we need to say before we start exploring the online casinos that accept American Express as a payment method. And this thing is that despite such casinos being reliable on their own, we make additional efforts to double-check them and make sure that every casino from the SlotsUp list has a valid license issued by one of the world's online gambling licensing institutions and has enough games for you to choose from and offers at least the introductory bonuses that can make your online gambling experience more entertaining and profitable. So, the only thing you must worry about is which website with the AMEX payment method to choose on this page, as there are so many of them that it can make you dizzy for a second.

Using this payment method to make a casino deposit is just as easy as using any other payment option and sometimes even easier. Just follow these simple steps toward the winnings:

1. Pick one of the casinos accepting American Express as a payment method from the SlotsUp list. We know it's not the easiest choice as there are quite a lot of such casinos here, so pay attention to whether the website is available at your location, what the choice of games is, what kind of bonuses it offers, is mobile-friendly, and other points important for you personally. Only some casinos may be perfect for you, but all the websites accepting this payment method and presented on this page are worth trying.

2. Create an account in the online casino or log in to the existing one if it's not your first time playing online gambling games on this website.

3. Go to the depositing section of the casino and choose AMEX as a payment method.

4. Enter the amount you want to deposit. American Express lets you make small and larger deposits, so it doesn't matter whether you are a beginner or a high roller: in any case, you can use this payment method on online gambling websites.

5. Enter your card details. You'd need to enter your card number, the expiration date, and the CVV number printed on the back of your Card. Don't worry about the security issues here, as you are playing on a reliable website using a reliable payment method.

6. Double-check everything, approve the transaction, and enjoy real money online gambling in a few moments. The AMEX payment usually takes little time to be completed, so now you can spend time playing instead of wondering what casinos accept American Express and waiting for the money to hit the account.

Making the American Express withdrawal is as easy as depositing using this payment method.

1. Choose a casino with the American Express withdrawal option. It's always better to check this information before you start playing and make your first deposit to ensure you can use the same withdrawal payment method. With American Express being a popular payment method and the SlotsUp list of gambling websites being constantly updated, there won't be any problems finding the one with the AMEX withdrawals.

2. Go to your account, have a fun minute looking at the amount you've won, and then choose the AMEX payment method to withdraw the money.

3. Enter the amount you want to withdraw and your American Express card details. Once again, the card number, expiration date, and CVV number are required.

4. Wait until the transaction is made and the money appears on your AMEX account. The American Express withdrawal time depends on the website and your bank, but usually, it won't take too long for the money to become available for use.

American Express has its pros and cons, like any other payment method, and the list of pros is different. We'll name a couple of advantages of using this payment method; the rest will be left for you to discover.

• When you use the AMEX payment method, your money and personal information are completely safe. The company uses the most advanced technologies to protect its customers, and we only enlist the top American Express casinos to make everything we can from our side to protect our readers.

• The deposits made with this payment method are fast. No more long hours of waiting until your money comes from your bank account to your online casino account — a couple of simple steps, and you can play your favorite games almost instantly.

• The choice of online casinos accepting this payment system for deposits lets you compare the websites and choose those that meet the quality criteria and those you like the most.

• This payment method makes you a part of one of the American Express reward programs that assign you bonus points when you bet on one of many online gambling websites.